Protective effects of Ca2+ channel blockers against methyl mercury toxicity.

@article{Sakamoto1996ProtectiveEO,
  title={Protective effects of Ca2+ channel blockers against methyl mercury toxicity.},
  author={Mineshi Sakamoto and Naohito Ikegami and A. Y. Nakano},
  journal={Pharmacology & toxicology},
  year={1996},
  volume={78 3},
  pages={193-9}
}
The protective effects of Ca2+ channel blockers against the toxicity of methyl mercury were examined by both in vivo and in vitro experiments. In the in vivo study we first examined the effects of the Ca2+ channel blockers (20 mg/kg/day), flunarizine, nifedipine, nicardipine, and verapamil against the toxic level of methyl mercury treatment (5 mg/kg/day of methyl mercuric chloride for 12 consecutive days). However, there was a difference in potency of the effects among the reagents. All the Ca2… CONTINUE READING

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