Protective effects of Acanthopanax polysaccharides on cerebral ischemia-reperfusion injury and its mechanisms.

@article{Xie2015ProtectiveEO,
  title={Protective effects of Acanthopanax polysaccharides on cerebral ischemia-reperfusion injury and its mechanisms.},
  author={Yunliang Xie and Bo Zhang and Yingjie Zhang},
  journal={International journal of biological macromolecules},
  year={2015},
  volume={72},
  pages={946-50}
}
A kind of Acanthopanax polysaccharides extracted from the root of Acanthioanax senticosus was named CASPs. The protective effect of CASPs on the cerebral ischemia-reperfusion injury was observed and the underlying mechanism was explored. Wistar male rats were randomly divided into six groups, namely, sham-operated group, model group, nimodipine group (15 mg/kg/day) and CASPs groups (50, 100 and 200 mg/kg/day). The suture method was used to embolize the middle cerebral artery to establish a rat… CONTINUE READING
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