Protective effects of ADAM8 against cisplatin-mediated apoptosis in non-small-cell lung cancer.


A disintegrin, metalloproteinase 8 (ADAM8), is overexpressed in the vast majority of lung cancers and can be a diagnostic marker of lung cancer. We have investigated the effect of ADAM8 on the cisplatin resistance in non-small-cell lung cancer (NSCLC) cell lines. Stable cell lines overexpressing ADAM8 in A549 and H460 cells were generated, both of which… (More)
DOI: 10.1002/cbin.10011


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