Protective effects of β-carotene against the genotoxicity of doxorubicin in somatic cells of Drosophila melanogaster

@inproceedings{Dias2009ProtectiveEO,
  title={Protective effects of β-carotene against the genotoxicity of doxorubicin in somatic cells of Drosophila melanogaster},
  author={C. D. Dias and Breno C Ara{\'u}jo and Elaine S. Dutra and J{\'u}lio C{\'e}sar Nepomuceno},
  year={2009}
}
β-carotene (BC), pro-vitamin A, is an efficient antioxidant, effective in the neutralization of oxygen reactive species, which cause serious damage to DNA. Various studies have been conducted on the effectiveness of BC for chemoprevention of cancer and heart disease. Doxorubicin is a chemotherapeutic agent used for cancer treatment that generates free radicals. We examined the effects of BC (1, 2 and 4 mg/mL) on the genotoxicity of doxorubicin (0.125 mg/mL), using the wing spot test in… CONTINUE READING
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