Protective effect of taurine against free radicals damage in the rat myocardium.

@article{Hanna2004ProtectiveEO,
  title={Protective effect of taurine against free radicals damage in the rat myocardium.},
  author={Jean Hanna and Ramez Chahine and Georges Aftimos and Moni Nader and A Mounayar and Fadi Esseily and Soulaima Chamat},
  journal={Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie},
  year={2004},
  volume={56 3},
  pages={189-94}
}
Free radicals are highly cytotoxic to the heart and are involved in ischemia/reperfusion injury. In this study, we tested the ability of taurine to neutralize the deleterious effects of free radicals generated ex vivo and in vitro. Taurine was added at a concentration of 0.1 mM to the drinking water of experimental rats during 6 months. The animal hearts were then isolated and submitted to regional ischemia and reperfusion; ventricular fibrillation was significantly reduced as compared to a… CONTINUE READING

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Mentioned Connections BETA
BuffersNo subtypeDyes
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
DyesNo subtypeBuffers
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
When isolated hearts were perfused with electrolysed buffer , extensive fiber necrosis occurred , as observed by staining with nitro blue tertrazolium , a soluble dye which yields a dark blue formazan stain in the presence of reducing agents This stain was barely detectable when taurine was added to the perfusing electrolysed buffer .
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