Protective effect of rutin against spatial memory impairment induced by trimethyltin in rats.

@article{Koda2008ProtectiveEO,
  title={Protective effect of rutin against spatial memory impairment induced by trimethyltin in rats.},
  author={Tomoko Koda and Yoshiki Kuroda and Hideki Imai},
  journal={Nutrition research},
  year={2008},
  volume={28 9},
  pages={
          629-34
        }
}
Rutin is a flavonoid with various biological activities that are beneficial to human health. Trimethyltin is a toxic organotin compound, and rats injected with trimethyltin serve as a useful in vivo model for studying spatial memory impairment and neurodegeneration in the hippocampus. The protective effect of rutin against the trimethyltin-induced spatial memory impairment and hippocampal neuron damage in rats was examined. Peroral administration of a single dose of trimethyltin (8.5 mg/kg… CONTINUE READING
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