Protective effect of olive oil minor polar components against oxidative damage in rats treated with ferric-nitrilotriacetate.

@article{Deiana2007ProtectiveEO,
  title={Protective effect of olive oil minor polar components against oxidative damage in rats treated with ferric-nitrilotriacetate.},
  author={Monica Deiana and Antonella Rosa and G R Leonel Corona and Angela Atzeri and Alessandra Incani and Francesco Visioli and M Paola Melis and M Assunta Dess{\`i}},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2007},
  volume={45 12},
  pages={
          2434-40
        }
}
The phenolic fraction of virgin olive oil exerts preventive effects against reactive oxygen species mediated degenerative diseases. To investigate its action as inhibitor of lipid peroxidation in vivo, we treated Wistar rats with olive oil minor polar components (MPC) (25-50 mg/kg bw) prior to the administration of a sublethal dose (15 mg Fe/kg bw) of ferric-nitrilotriacetate (Fe-NTA). Intraperitoneal injection (i.p.) of Fe-NTA lead to increased oxidative stress associated with extensive… CONTINUE READING
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