Protective effect of lycopene on cardiac function and myocardial fibrosis after acute myocardial infarction in rats via the modulation of p38 and MMP-9

@article{Wang2013ProtectiveEO,
  title={Protective effect of lycopene on cardiac function and myocardial fibrosis after acute myocardial infarction in rats via the modulation of p38 and MMP-9},
  author={Xin Wang and H. P. Lv and Yongwei Gu and Xi Wang and Hong L Cao and Yanhong Tang and Hui Chen and Cong-xin Huang},
  journal={Journal of Molecular Histology},
  year={2013},
  volume={45},
  pages={113-120}
}
Extracellular matrix (ECM) plays an important role in maintaining the left ventricular geometry and ventricular function, and the inhibition of ECM remodeling has therapeutic benefits that could alleviate the progression of ventricular remodeling. Recent studies have indicated that lycopene has cardioprotective effects. In this study, a rat myocardial infarction (MI) model was established by left anterior descending coronary artery ligation. After the operation, the rats received lycopene or… CONTINUE READING

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Higher dietary lycopene intake is associated with longer cardiac event-free survival in patients with heart failure.

European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology • 2013
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