Protective effect of ginsenoside-Re against cerebral ischemia/reperfusion damage in rats.

@article{Zhou2006ProtectiveEO,
  title={Protective effect of ginsenoside-Re against cerebral ischemia/reperfusion damage in rats.},
  author={Xiao-Mian Zhou and Ying-lin Cao and De-Qiang Dou},
  journal={Biological & pharmaceutical bulletin},
  year={2006},
  volume={29 12},
  pages={2502-5}
}
To investigate the protective effect of ginsenoside Re (Re) against cerebral ischemia-reperfusion injury, adult male Wistar rats weighing 250-300 g were subjected to either sham surgery or middle cerebral artery occlusion (MCAO) for 2 h of brain ischemia and 2 h reperfusion. A fluorescence polarization assay was carried out for membrane fluidity of brain mitochondria. Lipid peroxidation [malondiadehyde (MDA) formation], superoxide dismutase (SOD) and glutathion peroxidase (GSH-Px) of rat brain… CONTINUE READING
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