Protective effect of ellagic acid against TCDD-induced renal oxidative stress: Modulation of CYP1A1 activity and antioxidant defense mechanisms

@article{Padma2014ProtectiveEO,
  title={Protective effect of ellagic acid against TCDD-induced renal oxidative stress: Modulation of CYP1A1 activity and antioxidant defense mechanisms},
  author={Viswanadha Vijaya Padma and Palaniswamy Kalai Selvi and Samadi Sravani},
  journal={Molecular Biology Reports},
  year={2014},
  volume={41},
  pages={4223-4232}
}
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) belongs to toxicologically important class of poly halogenated aromatic hydrocarbons and produce wide variety of adverse effects in humans. The present study investigated the protective effect of ellagic acid, a natural polyphenolic compound against TCDD-induced nephrotoxicity in Wistar rats. TCDD-induced… CONTINUE READING