Protective effect of edaravone against hypoxia-reoxygenation injury in rabbit cardiomyocytes.

@article{Yamawaki2004ProtectiveEO,
  title={Protective effect of edaravone against hypoxia-reoxygenation injury in rabbit cardiomyocytes.},
  author={Masahiro Yamawaki and Norihito Sasaki and Masaki Shimoyama and Junichiro Miake and Kazuhide Ogino and Osamu Igawa and Fumito Tajima and Chiaki Shigemasa and Ichiro Hisatome},
  journal={British journal of pharmacology},
  year={2004},
  volume={142 3},
  pages={618-26}
}
1 We examined whether edaravone (Eda), a clinically available radical scavenger, directly protects cardiomyocytes from ischemia/reperfusion (I/R) injury, and whether the timing of its application is critical for protection. 2 Cardioprotective effects of edaravone were tested in the modified cell-pelleting model of ischemia and under exogenous oxidative… CONTINUE READING