Protective effect of chokeberry on chemical-induced oxidative stress in rat.

@article{Kujawska2011ProtectiveEO,
  title={Protective effect of chokeberry on chemical-induced oxidative stress in rat.},
  author={Małgorzata Kujawska and Ewa Ignatowicz and Małgorzata Ewertowska and Jan Oszmiański and Jadwiga Jodynis-Liebert},
  journal={Human & experimental toxicology},
  year={2011},
  volume={30 3},
  pages={199-208}
}
Male Wistar rats were treated with chokeberry juice per os, 10 mL/kg/day, for 28 days and a single intraperitoneal (i.p.) dose of N-nitrosodiethylamine (NDEA), 150 mg/kg, or carbon tetrachloride (CCl(4)), 2 ml/kg. The level of hepatic microsomal lipid peroxidation, expressed as thiobarbituric acid reactive substances (TBARS), was increased in animals dosed with NDEA and CCl(4). Juice pretreatment resulted in a significant decrease in TBARS by 53% and 92%, respectively. In rats administered… CONTINUE READING