Protective effect of boswellic acids versus pioglitazone in a rat model of diet-induced non-alcoholic fatty liver disease: influence on insulin resistance and energy expenditure

@article{Zaitone2015ProtectiveEO,
  title={Protective effect of boswellic acids versus pioglitazone in a rat model of diet-induced non-alcoholic fatty liver disease: influence on insulin resistance and energy expenditure},
  author={Sawsan Abo-Bakr Zaitone and Bassant M Barakat and Shymaa El-Shawadfy Bilasy and Manal S Fawzy and Eman Z. Abdelaziz and Noha E. Farag},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2015},
  volume={388},
  pages={587-600}
}
Non-alcoholic fatty liver disease (NAFLD) is closely linked to insulin resistance, oxidative stress, and cytokine imbalance. Boswellic acids, a series of pentacyclic triterpene molecules that are produced by plants in the genus Boswellia, has been traditionally used for the treatment of a variety of diseases. This study aimed at evaluating the protective effect of boswellic acids in a model of diet-induced NAFLD in rats in comparison to the standard insulin sensitizer, pioglitazone. Rats were… CONTINUE READING
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