Protective effect of biodegradable nerve conduit against peripheral nerve adhesion after neurolysis.

@article{Shintani2018ProtectiveEO,
  title={Protective effect of biodegradable nerve conduit against peripheral nerve adhesion after neurolysis.},
  author={Kosuke Shintani and Takuya Uemura and Kiyohito Takamatsu and Takuya Yokoi and Ema Onode and Mitsuhiro Okada and Hiroaki Nakamura},
  journal={Journal of neurosurgery},
  year={2018},
  volume={129 3},
  pages={
          815-824
        }
}
OBJECTIVE Peripheral nerve adhesion caused by extraneural and intraneural scar formation after neurolysis leads to nerve dysfunction. The authors previously developed a novel very flexible biodegradable nerve conduit composed of poly(L-lactide) and poly(ε-caprolactone) for use in peripheral nerve regeneration. In the present study, they investigated the effect of protective nerve wrapping on preventing adhesion in a rat sciatic nerve adhesion model. METHODS Rat sciatic nerves were randomly… CONTINUE READING