Protective effect of adenosine A2A receptor activation in small-for-size liver transplantation.

@article{Tang2007ProtectiveEO,
  title={Protective effect of adenosine A2A receptor activation in small-for-size liver transplantation.},
  author={Liming Tang and Y Wang and Ke Wang and Li-yong Pu and Feng Zhang and Xiang-cheng Li and Lian-bao Kong and Bei-cheng Sun and Guoqiang Li and Xue-hao Wang},
  journal={Transplant international : official journal of the European Society for Organ Transplantation},
  year={2007},
  volume={20 1},
  pages={93-101}
}
The aim of the present study was to investigate the potential role of adenosine A(2A) receptor (A(2A)R) activation in small-for-size liver transplantation. A rat orthotopic liver transplantation model was performed by using 40% (range: 36-46%) liver grafts. Recipients were given either saline (control group) or CGS 21680 (2-p-(2-Carboxyethyl)phenethylamino-5'-N-ethylcarboxamidoadenosine hydrochloride, a selective A(2A)R agonist), or CGS 21680+ ZM 241385 (a selective A(2A)R antagonist… CONTINUE READING