Protective effect of a water-soluble polysaccharide from Salvia miltiorrhiza Bunge on insulin resistance in rats.

@article{Zhang2012ProtectiveEO,
  title={Protective effect of a water-soluble polysaccharide from Salvia miltiorrhiza Bunge on insulin resistance in rats.},
  author={Wei Zhang and Lijuan Zheng and Zuo-Ming Zhang and Chunxu Hai},
  journal={Carbohydrate polymers},
  year={2012},
  volume={89 3},
  pages={890-8}
}
Oxidative stress is associated with insulin resistance (IR) and is thought to contribute to the development and progression toward type 2 diabetes (T2DM). This study was undertaken to isolate the bioactive polysaccharide (SMPW1) from Salvia miltiorrhiza Bunge and investigated its protective effects on IR model in rats induced by tert-butyl hydroperoxide (t-BHP). In vivo animal experiments showed that SMPW1 (50 and 100mg/kg) possessed high antioxidative and protective capacity against the injury… CONTINUE READING
7 Citations
30 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Glucose toxicity of the cell : Cellular and molecular mechanisms

  • R. P. Robertson, J. S. Harmon, Y. Tanaka, G. Sacchi, P. O. Tran, C. E. Gleason
  • 2000
Highly Influential
1 Excerpt

Effect of Salvia miltiorrhiza hydrophilic extract on antioxidant enzymes in diabetic patients with chronic heart disease : A randomized controlled trial

  • W. Rathmann, G. Giani
  • Phytotherapy Research
  • 2011

Protective effects of Salvia miltiorrhiza on rats with streptozotocin diabetes and its mechanism

  • O. H. Lowry, N. J. Rosebrough, A. L. Farr, R. J. Randall
  • Zhong Xi Yi Jie He Xue Bao
  • 2005

Are oxidative stressactivated signaling pathways mediators of IR and betacell dysfunction ?

  • T. M. C. C. ilisetti-Cozzi, N. C. Carpita
  • Diabetes
  • 2003

Similar Papers

Loading similar papers…