Protective effect of a prostaglandin oligomer on liver mitochondria in situ: time-shared measurements of fluorescence and reflectance in the cold-preserved rat liver

@article{Tokuka1992ProtectiveEO,
  title={Protective effect of a prostaglandin oligomer on liver mitochondria in situ: time-shared measurements of fluorescence and reflectance in the cold-preserved rat liver},
  author={A. Tokuka and A. Tanaka and T. Fujita and M. Hayashi and T. Kitai and Y. Yamaoka and K. Ozawa and S. Ohnishi},
  journal={Transplant International},
  year={1992},
  volume={5},
  pages={193-196}
}
The protective effect of a new oligomeric derivative of prostaglandin B2, known as OC-5186, was evaluated using time-sharing spectrofluorometry in the coldpreserved rat liver. Experiments were divided into three groups: in group A, a 5000 ng dose of OC-5186 was administered via the peripheral vein, 1000 ng via the portal vein, and 200 ng/ml in University of Wisconsin (UW) solution; in group B, the OC-5186 dosage was ten times greater than that in group A; in group C (control group), liver… Expand
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