Protective effect of Rehmannia glutinosa on the cisplatin-induced damage of HEI-OC1 auditory cells through scavenging free radicals.

@article{Yu2006ProtectiveEO,
  title={Protective effect of Rehmannia glutinosa on the cisplatin-induced damage of HEI-OC1 auditory cells through scavenging free radicals.},
  author={Hyeon-Hee Yu and Se-Jeong Seo and Yeon-hwa Kim and Hae-Youn Lee and Rae-Kil Park and Hong-Seob So and Seon Ll Jang and Yong-Ouk You},
  journal={Journal of ethnopharmacology},
  year={2006},
  volume={107 3},
  pages={383-8}
}
The steamed root of Rehmannia glutinosa has been used in traditional Oriental Medicine for treatment of inner ear diseases, such as tinnitus and hearing loss. In the present study, we showed that the ethanol extract of steamed roots of Rehmannia glutinosa (SRG) protected HEI-OC1 auditory cells from cisplatin cytotoxicity in a dose-dependent fashion. In addition, to investigate the protection mechanism of SRG on cisplatin cytotoxicity towards HEI-OC1, we measured the effects of SRG on lipid… CONTINUE READING

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