Protective effect of Platycodi radix on carbon tetrachloride-induced hepatotoxicity.

@article{Lee2002ProtectiveEO,
  title={Protective effect of Platycodi radix on carbon tetrachloride-induced hepatotoxicity.},
  author={K. Lee and H. Jeong},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2002},
  volume={40 4},
  pages={
          517-25
        }
}
  • K. Lee, H. Jeong
  • Published 2002
  • Chemistry, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
The protective effects of a Platycodi radix (Changkil: CK), the root of Platycodon grandiflorum A. DC (Campanulaceae) on carbon tetrachloride (CC14)-induced hepatotoxicity and the possible mechanisms involved in this protection were investigated in mice. Pretreatment with CK prior to the administration of CC14 significantly prevented the increased serum enzymatic activities of alanine and aspartate aminotransferase in a dose-dependent manner. In addition, pretreatment with CK also significantly… Expand
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