Protective effect of Platycodi radix on carbon tetrachloride-induced hepatotoxicity.

@article{Lee2002ProtectiveEO,
  title={Protective effect of Platycodi radix on carbon tetrachloride-induced hepatotoxicity.},
  author={Kyung Jin Lee and Hye Gwang Jeong},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2002},
  volume={40 4},
  pages={517-25}
}
The protective effects of a Platycodi radix (Changkil: CK), the root of Platycodon grandiflorum A. DC (Campanulaceae) on carbon tetrachloride (CC14)-induced hepatotoxicity and the possible mechanisms involved in this protection were investigated in mice. Pretreatment with CK prior to the administration of CC14 significantly prevented the increased serum enzymatic activities of alanine and aspartate aminotransferase in a dose-dependent manner. In addition, pretreatment with CK also significantly… CONTINUE READING