Protective effect of Astragalus corniculatus saponins against myeloid graffi tumour in hamsters.

@article{Krasteva2004ProtectiveEO,
  title={Protective effect of Astragalus corniculatus saponins against myeloid graffi tumour in hamsters.},
  author={Ilina Nikolaeva Krasteva and Reneta Aleksandrova Toshkova and Sp. D. Nikolov},
  journal={Phytotherapy research : PTR},
  year={2004},
  volume={18 3},
  pages={255-7}
}
A purified mixture containing mostly saponins (PMS) from Astragalus corniculatus Bieb. was used in an in vivo model to demonstrate its protective effect against myeloid Graffi tumour in hamsters. Survivability, tumour growth and tumour transplantability were followed. Comparative studies revealed that the intraperitoneal administration of PMS: (i) decreased the tumour transplantability; (ii) inhibited tumour growth in the early stages of tumour progression; (iii) increased the mean survival… CONTINUE READING