Protective antibody and cytokine responses in mice following immunization with recombinant beta-tubulin and subsequent Trypanosoma evansi challenge

@inproceedings{Tewari2015ProtectiveAA,
  title={Protective antibody and cytokine responses in mice following immunization with recombinant beta-tubulin and subsequent Trypanosoma evansi challenge},
  author={Anup Kumar Tewari and Samarchith P. Kurup and Surajit Baidya and J R Barta and Bijaya Sharma},
  booktitle={Parasites & Vectors},
  year={2015}
}
BackgroundTrypanosomosis or Surra, caused by the flagellated hemoprotozoan parasite Trypanosoma evansi, is a disease of economic importance through its wide prevalence in domestic livestock in tropical countries. In the absence of a protective vaccine, management of the disease relies on a few available chemotherapeutic agents. Although humoral immunity is the mainstay of resistance to T. evansi, the ability of the parasite to vary its immunodominant surface proteins to subvert the immune… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 45 REFERENCES

Induction of IgG2a class switching in B cells by IL-27.

  • Journal of immunology
  • 2004
VIEW 12 EXCERPTS
HIGHLY INFLUENTIAL

Current status of vaccination against African trypanosomiasis

S. Magez
  • Parasitology
  • 2017