Protective Roles of Interferon‐γ in Cardiac Hypertrophy Induced by Sustained Pressure Overload

@inproceedings{Kimura2018ProtectiveRO,
  title={Protective Roles of Interferon‐γ in Cardiac Hypertrophy Induced by Sustained Pressure Overload},
  author={Akihiko Kimura and Yuko Ishida and Machi Furuta and Mizuho Nosaka and Yumi Kuninaka and Akira Taruya and Naofumi Mukaida and Toshikazu Kondo},
  booktitle={Journal of the American Heart Association},
  year={2018}
}
BACKGROUND A clear understanding of the molecular mechanisms underlying hemodynamic stress-initiated cardiac hypertrophy is important for preventing heart failure. Interferon-γ (IFN-γ) has been suggested to play crucial roles in various diseases other than immunological disorders by modulating the expression of myriad genes. However, the involvement of IFN-γ in the pathogenesis of cardiac hypertrophy still remains unclear. METHODS AND RESULTS In order to elucidate the roles of IFN-γ in… CONTINUE READING
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