Protective Role for Properdin in Progression of Experimental Murine Atherosclerosis

@inproceedings{Steiner2014ProtectiveRF,
  title={Protective Role for Properdin in Progression of Experimental Murine Atherosclerosis},
  author={Tanja Steiner and Lorenza Francescut and Simon Byrne and Timothy Hughes and Archana Jayanthi and Irina A. Guschina and J. Harwood and Katherine Cianflone and Cordula Stover and Sheila Francis},
  booktitle={PloS one},
  year={2014}
}
Genetic, dietary and immune factors contribute to the pathogenesis of atherosclerosis in humans and mice. Complement activation is an integral part of the innate immune defence but also shapes cellular responses and influences directly triglyceride synthesis. Deficiency of Factor B of the alternative pathway (AP) of complement is beneficial in LDLR… CONTINUE READING