Protective Immunity and Safety of a Genetically Modified Influenza Virus Vaccine

  title={Protective Immunity and Safety of a Genetically Modified Influenza Virus Vaccine},
  author={Rafael Polidoro Alves Barbosa and Ana Paula Carneiro Salgado and Cristiana C Garcia and Bruno Galv{\~a}o Filho and Ana Paula de Faria Gonçalves and Braulio Henrique Freire Lima and Gabriel Augusto Oliveira Lopes and Milene Alvarenga Rachid and Andiara Cristina Cardoso Peixoto and Danilo Bretas de Oliveira and Marco Ant{\^o}nio Ata{\'i}de and Carla Aparecida Zirke and Tatiane Marques Cotrim and {\'E}rica Azevedo Costa and Gabriel Magno de Freitas Almeida and Remo C Russo and Ricardo Tostes Gazzinelli and Alexandre de Magalh{\~a}es Vieira Machado},
  booktitle={PloS one},
Recombinant influenza viruses are promising viral platforms to be used as antigen delivery vectors. To this aim, one of the most promising approaches consists of generating recombinant viruses harboring partially truncated neuraminidase (NA) segments. To date, all studies have pointed to safety and usefulness of this viral platform. However, some aspects of the inflammatory and immune responses triggered by those recombinant viruses and their safety to immunocompromised hosts remained to be… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 15 times over the past 90 days. VIEW TWEETS
4 Citations
55 References
Similar Papers


Publications referenced by this paper.
Showing 1-10 of 55 references

Similar Papers

Loading similar papers…