Protective Effects of the Ethanol Extract of Viola tianshanica Maxim against Acute Lung Injury Induced by Lipopolysaccharides in Mice.
@article{Wang2017ProtectiveEO,
title={Protective Effects of the Ethanol Extract of Viola tianshanica Maxim against Acute Lung Injury Induced by Lipopolysaccharides in Mice.},
author={Xue Ding Wang and Qiao-li Yang and Yu-zhu Shi and Bi-yu Hou and Shengqian Yang and Hua Huang and Li Zhang and Guan-hua Du},
journal={Journal of microbiology and biotechnology},
year={2017},
volume={27 9},
pages={
1628-1638
}
}Viola tianshanica Maxim, belonging to the Violaceae plant family, is traditionally used in Uighur medicine for treating pneumonia, headache, and fever. There is, however, a lack of basic understanding of its pharmacological activities. This study was designed to observe the effects of the ethanol extract (TSM) from Viola tianshanica Maxim on the inflammation response in acute lung injury (ALI) induced by LPS and the possible underlying mechanisms. We found that TSM (200 and 500 mg/kg…
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References
SHOWING 1-10 OF 30 REFERENCES
Bojesodok-eum, a Herbal Prescription, Ameliorates Acute Inflammation in Association with the Inhibition of NF-κB-Mediated Nitric Oxide and ProInflammatory Cytokine Production
- BiologyEvidence-based complementary and alternative medicine : eCAM
- 2012
Investigation of the effects of BSE on the induction of nitric oxide, prostaglandin E2, and proinflammatory cytokines that are caused by lipopolysaccharide (LPS) in murine macrophage cell line and on the paw edema formation in animals found its repression of LPS-inducible NF-κB activation was repression.
Protective effect of taraxasterol on acute lung injury induced by lipopolysaccharide in mice.
- Biology, MedicineInternational immunopharmacology
- 2014
Therapeutic Effect of Chung-Pae, an Experimental Herbal Formula, on Acute Lung Inflammation Is Associated with Suppression of NF-κB and Activation of Nrf2
- Biology, MedicineEvidence-based complementary and alternative medicine : eCAM
- 2013
The results evidenced a therapeutic effect of CP on ALI, in which differential regulation of the two key inflammatory factors, NF-κB and Nrf2, was involved.
The Phenolic Fraction of Mentha haplocalyx and Its Constituent Linarin Ameliorate Inflammatory Response through Inactivation of NF-κB and MAPKs in Lipopolysaccharide-Induced RAW264.7 Cells
- Biology, ChemistryMolecules
- 2017
Results suggested that MHP and linarin exerted a potent inhibitory effect on pro-inflammatory meditator and cytokines production via the inactivation of NF-κB and MAPKs, and they may serve as potential modulatory agents for the prevention and treatment of inflammatory diseases.
Inhibitory Effects of Benzaldehyde Derivatives from the Marine Fungus Eurotium sp. SF-5989 on Inflammatory Mediators via the Induction of Heme Oxygenase-1 in Lipopolysaccharide-Stimulated RAW264.7 Macrophages
- Biology, ChemistryInternational journal of molecular sciences
- 2014
The results indicated that the anti-inflammatory effects of these benzaldehyde derivatives in LPS-stimulated RAW264.7 macrophages were due to the inactivation of the NF-κB pathway.
Anti‐inflammatory effects of liquiritigenin as a consequence of the inhibition of NF‐κB‐dependent iNOS and proinflammatory cytokines production
- MedicineBritish journal of pharmacology
- 2008
The effects of liquiritigenin on the induction of inducible NOS (iNOS) and proinflammatory cytokines by lipopolysaccharide (LPS) in Raw264.7 cells, and on paw oedema in rats are investigated.
Ceftiofur attenuates lipopolysaccharide-induced acute lung injury.
- Medicine, BiologyInternational immunopharmacology
- 2010
Protective effects of imipramine in murine endotoxin-induced acute lung injury.
- Biology, MedicineEuropean journal of pharmacology
- 2010
PARP-1 Inhibitor, DPQ, Attenuates LPS-Induced Acute Lung Injury through Inhibiting NF-κB-Mediated Inflammatory Response
- Biology, MedicinePloS one
- 2013
Results show that DPQ treatment inhibits NF-κB signaling in macrophages and protects mice against ALI induced by LPS, suggesting inhibition of Poly (ADP-ribose) polymerase-1 may be a potential and effective approach to resolve inflammation for the treatment of ALI.
The açaí flavonoid velutin is a potent anti-inflammatory agent: blockade of LPS-mediated TNF-α and IL-6 production through inhibiting NF-κB activation and MAPK pathway.
- BiologyThe Journal of nutritional biochemistry
- 2012







