Protective Effects of Lactic Acid Bacteria Against TLR4 Induced Inflammatory Response in Hepatoma HepG2 Cells Through Modulation of Toll-Like Receptor Negative Regulators of Mitogen-Activated Protein Kinase and NF-κB Signaling

@inproceedings{Kanmani2018ProtectiveEO,
  title={Protective Effects of Lactic Acid Bacteria Against TLR4 Induced Inflammatory Response in Hepatoma HepG2 Cells Through Modulation of Toll-Like Receptor Negative Regulators of Mitogen-Activated Protein Kinase and NF-κB Signaling},
  author={Paulraj Kanmani and Hojun Kim},
  booktitle={Front. Immunol.},
  year={2018}
}
The beneficial effects of probiotics in several liver diseases have been investigated in both animal and clinical models; however, the precise mechanisms responsible for their effects have not yet been elucidated. Gut transmitted endotoxins such as LPS have been shown to play critical roles in hepatic inflammation and injury. Therefore, in this study, we investigated the beneficial role of selected lactic acid bacteria (LABs) on reduction of hepatic steatosis (HS) and attenuation of LPS induced… CONTINUE READING
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Immunobiotic Bifidobacteria strains protect against rotavirus infection in porcine intestinal epitheliocytes via regulation of antiviral pattern recognition receptor signaling

  • T Ishizuka, P Kanmani, K Kobayashi, A Miyazaki, J Soma, Y Suda
  • PLoS One
  • 2016

an in vitro model of non-alcoholic fatty liver disease

  • MJ Alkhatatbeh, LF Lincz, cells Thorne RF. Low simvastatin concentrations reduce o HepG2
  • Exp Ther Med
  • 2016
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