Protective Effects of Kojic Acid on the Periphery Blood and Survival of Beagle Dogs after Exposure to a Lethal Dose of Gamma Radiation

@inproceedings{Wang2014ProtectiveEO,
  title={Protective Effects of Kojic Acid on the Periphery Blood and Survival of Beagle Dogs after Exposure to a Lethal Dose of Gamma Radiation},
  author={Kai Wang and Peng-fei Li and Chun-guang Han and L. Du and Chao Liu and Ming Hu and Shi Lian and Yong-xue Liu},
  booktitle={Radiation research},
  year={2014}
}
In previous studies, it has been shown that pretreatment with kojic acid (KA) not only increased the 30 day survival rate of mice after exposed to a lethal dose of gamma radiation but also had significant radioprotective effects on the hematopoietic system, the immune system and DNA of mice exposed to a 4 Gy sublethal dose of radiation. Furthermore, pretreatment with KA has also been shown to protect Chinese hamster ovary (CHO) cells against ionizing radiation-induced damage. In this… 
Efficacy of tea polyphenols (TP 50) against radiation-induced hematopoietic and biochemical alterations in beagle dogs.
TLDR
Oral administration of TP 50 to beagle dogs effectively alleviated hematopoietic bone marrow dam- age induced by γ-radiation, and TP 50 repaired radiation-induced organ damage.
Diallyl Disulfide Mitigates DNA Damage and Spleen Tissue Effects After Irradiation
  • T. Nakajima, G. Vares, M. Nenoi
  • Medicine, Biology
    Medical science monitor : international medical journal of experimental and clinical research
  • 2019
TLDR
DADS is a potential radiation-protective agent that effectively mitigates DNA damage, and its effects in the spleen observed after irradiation may be related to inflammation and carcinogenesis.
Kojic acid applications in cosmetic and pharmaceutical preparations.
AMEDMENT STABLE KOJIC ACID PRODUCED BY NON-TOXINOGENIC ASPERGILLUS ORYZAE USING FIVE LEVELS CENTRAL COMPOSITE DESIGN OF RESPONSE SURFACE METHODOLOGY
Kojic acid is a remarkable secondary metabolite of Aspergillus with various hot spot applications in the field of medicine, cosmetics, food, agriculture, and chemistry field. However the needs of

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