Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat

@inproceedings{Carr2009ProtectiveEO,
  title={Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat},
  author={Amanda-Jayne F Carr and Anthony A. Vugler and Sherry T. Hikita and Jean M. Lawrence and Carlos Gias and Li Li Chen and David E. Buchholz and Ahmad Ahmado and Ma'ayan Semo and Matthew James Smart and S M Mahmudul Hasan and Lyndon da Cruz and Lincoln V. Johnson and Dennis O Clegg and Pete J. Coffey},
  booktitle={PloS one},
  year={2009}
}
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs). These induced pluripotent stem (iPS) cells have the potential to differentiate into any cell type, making them a potential source from which to produce cells as a therapeutic platform for the treatment of a wide range of diseases. In many forms of human retinal disease, including age-related macular degeneration (AMD), the underlying… CONTINUE READING

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