Protective Effects of Ellagic Acid on Cardiovascular Injuries Caused by Hypertension in Rats.

  title={Protective Effects of Ellagic Acid on Cardiovascular Injuries Caused by Hypertension in Rats.},
  author={J. Jord{\~a}o and H. Porto and F. Lopes and A. Batista and M. Rocha},
  journal={Planta medica},
  volume={83 10},
  • J. Jordão, H. Porto, +2 authors M. Rocha
  • Published 2017
  • Medicine
  • Planta medica
  • Ellagic acid is described as having antioxidant and antiproliferative properties. Hence, it was hypothesized that ellagic acid could improve cardiovascular damage caused by hypertension. In this work, hypertension was induced in rats with Nω-Nitro-L-arginine methyl ester hydrochloride (60 mg/kg/day in drinking water) for 6 weeks. Ellagic acid was coadministered (10 or 30 mg/kg/day by gavage) between the second and sixth week. Blood pressure was recorded every week by tail-cuff plethysmography… CONTINUE READING
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