Protective Effects of Curcumin against Sodium Arsenite-induced Ovarian Oxidative Injury in a Mouse Model

@inproceedings{Wang2017ProtectiveEO,
  title={Protective Effects of Curcumin against Sodium Arsenite-induced Ovarian Oxidative Injury in a Mouse Model},
  author={Xiaohui Wang and Chang-jun Zhang and Hong-Lu Diao and Ying Zhang},
  booktitle={Chinese medical journal},
  year={2017}
}
BACKGROUND Excessive reactive oxygen species (ROS) may lead to a number of reproductive diseases such as polycystic ovary syndrome. This study aimed to establish an animal model of ovarian oxidative stress and to assess the protective effect of curcumin against oxidative injury. METHODS Ovarian oxidative stress was induced in female Kunming mice (n = 40) with intraperitoneal injection of 8 mg/kg sodium arsenite (As) once every other day for 16 days; meanwhile, they were, respectively, treated… CONTINUE READING
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