Protective Effects of Crocus Sativus L. Extract and Crocin against Chronic-Stress Induced Oxidative Damage of Brain, Liver and Kidneys in Rats.

@article{Bandegi2014ProtectiveEO,
  title={Protective Effects of Crocus Sativus L. Extract and Crocin against Chronic-Stress Induced Oxidative Damage of Brain, Liver and Kidneys in Rats.},
  author={Ahmad Reza Bandegi and Ali Rashidy-pour and Abbas Ali Vafaei and Behshid Ghadrdoost},
  journal={Advanced pharmaceutical bulletin},
  year={2014},
  volume={4 Suppl 2},
  pages={493-9}
}
PURPOSE Chronic stress has been reported to induce oxidative damage of the brain. A few studies have shown that Crocus Sativus L., commonly known as saffron and its active constituent crocin may have a protective effect against oxidative stress. The present work was designed to study the protective effects of saffron extract and crocin on chronic - stress induced oxidative stress damage of the brain, liver and kidneys. METHODS Rats were injected with a daily dose of saffron extract (30 mg/kg… CONTINUE READING

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