Protective Effect of a Synbiotic against Multidrug-Resistant Acinetobacter baumannii in a Murine Infection Model.

@article{Asahara2016ProtectiveEO,
  title={Protective Effect of a Synbiotic against Multidrug-Resistant Acinetobacter baumannii in a Murine Infection Model.},
  author={Takashi Asahara and Akira Takahashi and Norikatsu Yuki and Rumi Kaji and Takuya Takahashi and Koji Nomoto},
  journal={Antimicrobial agents and chemotherapy},
  year={2016},
  volume={60 5},
  pages={
          3041-50
        }
}
This study investigated the ability of the probiotic Bifidobacterium breve strain Yakult (BbY) to protect against infection, as well as the potentiation of BbY activity by the synbiotic combination of BbY and prebiotic galactooligosaccharides (GOS). The study employed a mouse model of lethal intestinal multidrug-resistant Acinetobacter baumannii (MDRAb) infection. The endogenous intestinal microbiota was disrupted by the administration of multiple antibiotics, causing the loss of endogenous… CONTINUE READING
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