Protective Effect of Silybum marianum and Silibinin on Endothelial Cells Submitted to High Glucose Concentration.
@article{Palomino2017ProtectiveEO, title={Protective Effect of Silybum marianum and Silibinin on Endothelial Cells Submitted to High Glucose Concentration.}, author={O. Palomino and N. M. Gouveia and S. Ramos and M. Mart{\'i}n and L. Goya}, journal={Planta medica}, year={2017}, volume={83 1-02}, pages={ 97-103 } }
Silybum marianum Gaertn. (Milk thistle) has been used since ancient times for the relief of liver diseases characterized by intense oxidative stress such as inflammatory liver disease and cirrhosis. As oxidative stress by hyperglycemia is involved in micro- and macrovascular complications of type 2 diabetes, our aim was to assess the protective effect of milk thistle seed extract against oxidative stress induced by a high glucose concentration on endothelial cells (EA.hy926 cells). High… Expand
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References
SHOWING 1-10 OF 31 REFERENCES
Chemo-protective activity and characterization of phenolic extracts from Corema album
- Chemistry
- 2012
- 24
- PDF
Cocoa flavonoid epicatechin protects pancreatic beta cell viability and function against oxidative stress.
- Biology, Medicine
- Molecular nutrition & food research
- 2014
- 79
- PDF
Milk thistle in liver diseases: past, present, future
- Biology, Medicine
- Phytotherapy research : PTR
- 2010
- 340
- PDF
Silymarin, the antioxidant component and Silybum marianum extracts prevent liver damage.
- Chemistry, Medicine
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- 2010
- 233
Silibinin alleviates N-nitrosodimethylamine-induced glutathione dysregulation and hepatotoxicity in rats.
- Medicine
- Chinese journal of natural medicines
- 2016
- 14
Cocoa flavonoids protect hepatic cells against high-glucose-induced oxidative stress: relevance of MAPKs.
- Biology, Medicine
- Molecular nutrition & food research
- 2015
- 57
- PDF
Procyanidin B2 and a cocoa polyphenolic extract inhibit acrylamide-induced apoptosis in human Caco-2 cells by preventing oxidative stress and activation of JNK pathway.
- Chemistry, Medicine
- The Journal of nutritional biochemistry
- 2011
- 98
- PDF
Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells
- Chemistry, Medicine
- European journal of nutrition
- 2011
- 52
- PDF