Protective Effect of Rutin against Cisplatin-Induced Nephrotoxicity in Rats

@article{Sreedevi2010ProtectiveEO,
  title={Protective Effect of Rutin against Cisplatin-Induced Nephrotoxicity in Rats},
  author={Adikay Sreedevi and K. Divya Bharathi and K V Prasad},
  journal={Journal of Natural Remedies},
  year={2010},
  volume={10},
  pages={144-151}
}
Objective: To study the nephroprotector activity of the bioflavonoid, rutin (50 and 100 mg/kg, p.o.) on cisplatininduced nephrotoxicity (6mg/kg, i.p.) in albino rats. Materials and Methods: Nephroprotector activity of rutin was assessed by estimating the levels of blood urea nitrogen, serum creatinine, serum total proteins, urinary protein, creatinine clearance, urine to serum creatinine ratio and lipid peroxidation in kidney. Results: Cisplatin elevated the serum markers level, increased the… 

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