Protective Effect of L-Theanine on Haloperidol-Induced Orofacial.

  title={Protective Effect of L-Theanine on Haloperidol-Induced Orofacial.},
  author={Cheng-Neng Chen and Kuo Chi Chang and Mao-Hsien Wang and Hsiang-Chien Tseng and Hung-Sheng Soung},
  journal={The Chinese journal of physiology},
  volume={61 1},
Tardive dyskinesia (TD) is a severe side effect of chronic neuroleptic treatment consisting of abnormal involuntary movements, characterized by orofacial dyskinesia (OD). Haloperidol (HAL)- induced OD has been widely used as an animal model to study the neuropathophysiology of human TD with its pathophysiology strongly associated with striatal oxidative stress. L-Theanine (LT), one of the major amino acid components in green tea, has potent antioxidative effects and is able to protect against… 
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