Protective Effect of Heat Shock Protein 70 Against Oxidative Stresses in Human Corneal Fibroblasts

@inproceedings{Kim2004ProtectiveEO,
  title={Protective Effect of Heat Shock Protein 70 Against Oxidative Stresses in Human Corneal Fibroblasts},
  author={Yun-Sang Kim and Jung-Ah Han and Tae-Bum Cheong and Jae-Chun Ryu and Jihong Kim},
  booktitle={Journal of Korean medical science},
  year={2004}
}
We evaluated DNA protection effect of heat shock protein (HSP) against cytotoxic effects of exogenous nitric oxide (NO) and reactive oxygen intermediate (ROI). Cultured human corneal fibroblasts were divided into 4 groups. Control (Group I) was not exposed to a sub-lethal heat treatment. Other 3 groups were exposed to 43 degrees C for 1 hr, then incubated at 37 degrees C during different duration (1, 6, 24 hr, Group II, III, IV, respectively). Expression pattern of HSP 70 was analyzed by… CONTINUE READING

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