Protective Effect of Fucoxanthin against UVB-Induced Skin Photoaging in Hairless Mice

@article{Urikura2011ProtectiveEO,
  title={Protective Effect of Fucoxanthin against UVB-Induced Skin Photoaging in Hairless Mice},
  author={Itaru Urikura and Tatsuya Sugawara and Takashi Hirata},
  journal={Bioscience, Biotechnology, and Biochemistry},
  year={2011},
  volume={75},
  pages={757 - 760}
}
Fucoxanthin, a major carotenoid in brown algae, has various beneficial effects. In this study, we evaluated the effect of topical fucoxanthin on UVB-induced skin photoaging in hairless mice. The dorsal skins were treated topically with a 0.001% fucoxanthin solution 2 h each time before UVB irradiation (5 times a week) for 10 weeks. The formation of wrinkles in UVB-irradiated skin treated with vehicle alone significantly increased, as compared with the non-irradiated control. Treatment with… 

Preventive effect of dietary astaxanthin on UVA-induced skin photoaging in hairless mice

The results indicate that dietary astaxanthin accumulates in the skin and appears to prevent the effects of UVA irradiation on filaggrin metabolism and desquamation in the epidermis and the extracellular matrix in the dermis.

Title Preventive effect of dietary astaxanthin on UVA-induced skinphotoaging in hairless mice

The results indicate that dietary astaxanthin accumulates in the skin and appears to prevent the effects of UVA irradiation on filaggrin metabolism and desquamation in the epidermis and the extracellular matrix in the dermis.

Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice

FX, administered in a topical formulation, could be a novel natural adjuvant for preventing exacerbations associated with skin inflammatory pathologies as well as protecting skin against UV radiation.

Preventive effect of fermented Gelidium amansii and Cirsium japonicum extract mixture against UVB-induced skin photoaging in hairless mice

Oral administration of FGCM exerts potent anti-photoaging activities by improving wrinkle formation and dryness and suppression of UVB-induced epidermal thickening and MMP-13 expression in dermal tissue.

Inhibitory effect of Mojaban (Sargassum fulvellum) extract on ultraviolet B-induced photoaging in hairless mouse skin

Phenotypically, SFE reduced wrinkle formation and epidermal thickness and increased skin elasticity, and SFE increased hydroxyproline content by upregulating the expression of collagen-related genes and downregulating matrix metalloproteinase expression.

Potential for tyndalized Lactobacillus acidophilus as an effective component in moisturizing skin and anti-wrinkle products.

It was determined that tyndalized L. acidophilus effectively inhibited the wrinkle formation induced by UVB irradiation, and that this may be attributed to the downregulation of MMPs.

Orally administered betaine reduces photodamage caused by UVB irradiation through the regulation of matrix metalloproteinase-9 activity in hairless mice.

Investigation of the preventive effects of betaine on ultraviolet B (UVB) irradiation‑induced skin damage in hairless mice suggested that betaine inhibits UVB‑ induced skin damage by suppressing increased expression of MMP‑9 through the inhibition of MEK and ERK.
...

References

SHOWING 1-10 OF 32 REFERENCES

Protective effect of fucoxanthin isolated from Sargassum siliquastrum on UV-B induced cell damage.

  • S. HeoY. Jeon
  • Chemistry, Biology
    Journal of photochemistry and photobiology. B, Biology
  • 2009

Vascular endothelial growth factor promotes sensitivity to ultraviolet B-induced cutaneous photodamage.

It is revealed that V EGF promotes the cutaneous damage that occurs after UVB exposure and that the VEGF signaling pathway might serve as a novel target for the prevention of UVB-induced photodamage.

Antiangiogenic activity of brown algae fucoxanthin and its deacetylated product, fucoxanthinol.

Results imply that fucoxanthin having antiangiogenic activity might be useful in preventing angiogenesis-related diseases.

Targeted overexpression of the angiogenesis inhibitor thrombospondin-1 in the epidermis of transgenic mice prevents ultraviolet-B-induced angiogenesis and cutaneous photo-damage.

An important role of the cutaneous vascular system is revealed in mediating ultraviolet-B-induced skin damage and inhibition of angiogenesis is suggested as a potential new approach for the prevention of chronic cutaneous photo-damage.

Role of antioxidants in the skin: anti-aging effects.

  • H. Masaki
  • Biology
    Journal of dermatological science
  • 2010

Neutrophil Infiltration in Normal Human Skin After Exposure to Different Ultraviolet Radiation Sources

When the spectra emitted by the different UV sources were compared UVB seemed to be more effective than UVA in inducing neutrophil infiltration, suggesting that longer wavelengths within the UVB range are mostly responsible for the infiltration of neutrophils in the UV‐irradiated skin.

A review of skin ageing and its medical therapy

Recent work has substantially elucidated the ageing processes that affect the skin and has demonstrated that many of unwanted changes can be improved by topical therapy.