Protection of the neonatal heart following normothermic ischemia: a comparison of oxygenated saline and oxygenated versus nonoxygenated cardioplegia.

@article{Lynch1988ProtectionOT,
  title={Protection of the neonatal heart following normothermic ischemia: a comparison of oxygenated saline and oxygenated versus nonoxygenated cardioplegia.},
  author={Matthew James Lynch and Edward L. Bove and Thomas N. Zweng and Miguel Jos{\'e} Hagerty Fox and Steven F. Bolling and Kim P. Gallagher},
  journal={The Annals of thoracic surgery},
  year={1988},
  volume={45 6},
  pages={
          650-5
        }
}
Optimal methods of myocardial preservation in the neonate remain unknown. Hypothermia and cardioplegia have been shown to protect neonatal hearts, but few studies have examined the effects of cardioplegia when administered at normothermia. Accordingly, the role of 37 degrees C St. Thomas' cardioplegic solution in protecting the neonatal heart during 1 hour of ischemia in an isolated working rabbit heart model was examined. Both oxygenated and nonoxygenated cardioplegic solutions (CSs) were… CONTINUE READING
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