Protection of retinal ganglion cells against glaucomatous neuropathy by neurotrophin-producing, genetically modified neural progenitor cells in a rat model.

@article{Wang2002ProtectionOR,
  title={Protection of retinal ganglion cells against glaucomatous neuropathy by neurotrophin-producing, genetically modified neural progenitor cells in a rat model.},
  author={Ning Li Lu Wang and Mingbing Zeng and Yiwen Ruan and Heping Wu and Jingchang Chen and Zhigang Fan and Huling Zhen},
  journal={Chinese medical journal},
  year={2002},
  volume={115 9},
  pages={1394-400}
}
OBJECTIVE To investigate in vivo survival of retinal ganglion cells (RGCs) after partial blockage of optic nerve (ON) axoplasmic flow by sub-retinal space or vitreous cavity injection of brain-derived neural factor (BDNF) produced by genetically modified neural progenitor cells (NPCs). METHODS Adult Sprague-Dawley (SD) rat RGCs were labeled with granular… CONTINUE READING