Protection of pancreatic beta-cells from various stress conditions is mediated by DJ-1.

@article{Inberg2010ProtectionOP,
  title={Protection of pancreatic beta-cells from various stress conditions is mediated by DJ-1.},
  author={Alex Inberg and Michal Linial},
  journal={The Journal of biological chemistry},
  year={2010},
  volume={285 33},
  pages={25686-98}
}
Pancreatic beta-cells are vulnerable to multiple stresses, leading to dysfunction and apoptotic death. Deterioration in beta-cells function and mass is associated with type 2 diabetes. Comparative two-dimensional gel electrophoresis from pancreatic MIN6 cells that were maintained at varying glucose concentrations was carried out. An induced expression of a protein spot, detected in MIN6 cells experiencing high glucose concentration, was identified by mass spectrometry as the oxidized form of DJ… CONTINUE READING
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DJ-1 in Pancreatic -Cells

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Pancreatic -Cells 25698 JOURNAL OF BIOLOGICAL CHEMISTRY

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