Protection of newborn mice against herpes simplex virus infection by prenatal and postnatal transmission of antibody.

@article{Hayashi1983ProtectionON,
  title={Protection of newborn mice against herpes simplex virus infection by prenatal and postnatal transmission of antibody.},
  author={Yoshitake Hayashi and Teiji Wada and Ryoichi Mori},
  journal={The Journal of general virology},
  year={1983},
  volume={64 Pt 5},
  pages={1007-12}
}
Pre- and postnatally acquired protection against herpes simplex virus type 2(HSV-2) infection mediated by maternal antibody was investigated in the newborn mouse. Newborn mice, 2 days old, were inoculated with HSV-2 intraperitoneally after maternal immunization with live or inactivated virus. The survival rates improved in proportion to the maternal neutralizing antibody titres. Ninety-three percent of animals delivered by Caesarean section from immune mothers and suckled by non-immune mothers… CONTINUE READING

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