Protection of neutropenic mice from lethal Candida albicans infection by recombinant interleukin 1.

@article{Wout1988ProtectionON,
  title={Protection of neutropenic mice from lethal Candida albicans infection by recombinant interleukin 1.},
  author={Jan W van't Wout and Jos W M van der Meer and Michael Barza and Charles A Dinarello},
  journal={European journal of immunology},
  year={1988},
  volume={18 7},
  pages={1143-6}
}
Natural and synthetic immunomodulators that increase nonspecific resistance to infection are also known to induce interleukin 1 (IL 1) production. Previous studies have demonstrated a protective effect of recombinant human IL 1 beta against death from infection caused by Pseudomonas aeruginosa. In the present study we investigated the effect of IL 1 beta or IL 1 alpha on the survival of neutropenic mice with a lethal Candida albicans infection. Mice with cyclophosphamide-induced neutropenia… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

Inflammasome Signaling and Bacterial Infections

Current Topics in Microbiology and Immunology • 2016

Similar Papers

Loading similar papers…