Protection of mice from Mycobacterium tuberculosis by ID87/GLA-SE, a novel tuberculosis subunit vaccine candidate.

@article{Windish2011ProtectionOM,
  title={Protection of mice from Mycobacterium tuberculosis by ID87/GLA-SE, a novel tuberculosis subunit vaccine candidate.},
  author={Hillarie Plessner Windish and Malcolm S Duthie and Ayesha Misquith and Greg C. Ireton and Elyse Lucas and John D. Laurance and Remy H. Bailor and Rhea N Coler and Steven G Reed},
  journal={Vaccine},
  year={2011},
  volume={29 44},
  pages={
          7842-8
        }
}
  • Hillarie Plessner Windish, Malcolm S Duthie, +6 authors Steven G Reed
  • Published in Vaccine 2011
  • Biology, Medicine
  • Tuberculosis is a major health concern. Non-living tuberculosis (TB) vaccine candidates may not only be safer than the current vaccine (BCG) but could also be used to boost BCG to enhance or elongate protection. No subunit vaccines, however, are currently available for TB. To address this gap and to improve the global TB situation, we have generated a defined subunit vaccine by genetically fusing the genes of 3 potent protein Mtb antigens, Rv2875, Rv3478 and Rv1886, into a single product: ID87… CONTINUE READING

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