Protection of mice against Brucella abortus 544 challenge by vaccination with recombinant OMP28 adjuvanted with CpG oligonucleotides

@article{Kaushik2009ProtectionOM,
  title={Protection of mice against Brucella abortus 544 challenge by vaccination with recombinant OMP28 adjuvanted with CpG oligonucleotides},
  author={Purushottam Kaushik and Dhirendra Kumar Singh and Shalini V Kumar and Ashok Tiwari and Gunjan Shukla and Shanker Dayal and Pallav Chaudhuri},
  journal={Veterinary Research Communications},
  year={2009},
  volume={34},
  pages={119-132}
}
Brucella abortus, a gram negative, facultative intracellular pathogen causes brucellosis in many animal species and humans. Although live, attenuated vaccines are available against this infection, they suffer from certain limitations. Therefore, the development of an effective subunit vaccine against brucellosis is an area of intense research. The outer membrane proteins (OMPs) of Brucella species have been extensively studied for its immunogenicity and protective ability. We have investigated… CONTINUE READING
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