Protection of NAD(P)H:quinone oxidoreductase 1 against renal ischemia/reperfusion injury in mice.

@article{Gang2014ProtectionON,
  title={Protection of NAD(P)H:quinone oxidoreductase 1 against renal ischemia/reperfusion injury in mice.},
  author={Gil-Tae Gang and Jung Hwan Hwang and Yong-Hoon Kim and J. K. Noh and Kyoung-Shim Kim and Jin Young Jeong and Dae Eun Choi and Kang Wook Lee and Ju-Young Jung and Minho Shong and Chul-Ho Lee},
  journal={Free radical biology & medicine},
  year={2014},
  volume={67},
  pages={
          139-49
        }
}
UNLABELLED Ischemia/reperfusion (I/R) is the most common cause of acute renal injury. I/R-induced reactive oxygen species (ROS) are thought to be a major factor in the development of acute renal injury by promoting the initial tubular damage. NAD(P)H quinone oxidoreductase 1 (NQO1) is a well-known antioxidant protein that regulates ROS generation. The purpose of this study was to investigate whether NQO1 modulates the renal I/R injury (IRI) associated with NADPH oxidase (NOX)-derived ROS… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 23 CITATIONS

Pretreatment with Cholecalciferol Alleviates Renal Cellular Stress Response during Ischemia/Reperfusion-Induced Acute Kidney Injury

  • Oxidative medicine and cellular longevity
  • 2019
VIEW 10 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED