Protection from pneumonic infection with burkholderia species by inhalational immunotherapy.

@article{Goodyear2009ProtectionFP,
  title={Protection from pneumonic infection with burkholderia species by inhalational immunotherapy.},
  author={Andrew W. Goodyear and Lisa M Kellihan and Helle Bielefeldt-Ohmann and Ryan M. Troyer and Katie Propst and Steven Dow},
  journal={Infection and immunity},
  year={2009},
  volume={77 4},
  pages={1579-88}
}
Burkholderia mallei and B. pseudomallei are important human pathogens and cause the diseases glanders and melioidosis, respectively. Both organisms are highly infectious when inhaled and are inherently resistant to many antimicrobials, thus making it difficult to treat pneumonic Burkholderia infections. We investigated whether it was possible to achieve rapid protection against inhaled Burkholderia infection by using inhaled immunotherapy. For this purpose, cationic liposome DNA complexes (CLDC… CONTINUE READING
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