Protection from CMV infection in immunodeficient hosts by adoptive transfer of memory B cells.

@article{Klenovsek2007ProtectionFC,
  title={Protection from CMV infection in immunodeficient hosts by adoptive transfer of memory B cells.},
  author={Karin Klenovsek and Florian J. Weisel and Andrea M. Schneider and Uwe Kurt Appelt and Stipan Jonji{\'c} and Martin Messerle and Birgit G Bradel-Tretheway and Thomas H. Winkler and Michael Mach},
  journal={Blood},
  year={2007},
  volume={110 9},
  pages={3472-9}
}
Severe disease associated with cytomegalovirus (CMV) infection is still a major problem in patients who undergo transplantation. Support of the patients' immune defense against the virus is a major goal in transplantation medicine. We have used the murine model of CMV (MCMV) to investigate the potential of a cell-based strategy to support the humoral antiviral immune response. Immunocompetent C57BL/6 mice were infected with MCMV, and memory B cells from the immune animals were adoptively… CONTINUE READING

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