Protection by paracetamol against various gastric irritants in the rat.

@article{Kolfschoten1983ProtectionBP,
  title={Protection by paracetamol against various gastric irritants in the rat.},
  author={A A van Kolfschoten and Pieter Zandberg and Lowie P. Jager and J van Noordwijk},
  journal={Toxicology and applied pharmacology},
  year={1983},
  volume={69 1},
  pages={37-42}
}
Four nonsteroid anti-inflammatory drugs (NSAID), indomethacin, phenylbutazone, ibuprofen, and glafenine, caused erosions in the rat stomach in a dose-dependent manner. Paracetamol, which has been shown to protect against the gastric erosive activity of aspirin, reduced the gastric toxicity of indomethacin but was ineffective against the erosive activity of… CONTINUE READING