Protection by milk immunoglobulin concentrate against oral challenge with enterotoxigenic Escherichia coli.

@article{Tacket1988ProtectionBM,
  title={Protection by milk immunoglobulin concentrate against oral challenge with enterotoxigenic Escherichia coli.},
  author={Carol O. Tacket and Genevieve Losonsky and Hans Link and Yen Hoang and Pierre Guesry and H R Hilpert and Myron M. Levine},
  journal={The New England journal of medicine},
  year={1988},
  volume={318 19},
  pages={1240-3}
}
Enterotoxigenic Escherichia coli is a common cause of traveler's diarrhea. Prophylaxis against traveler's diarrhea has been associated with side effects from bismuth subsalicylate and the development of resistance to antimicrobial agents. We undertook a double-blind controlled trial in which a bovine milk immunoglobulin concentrate with high titers of antibodies against enterotoxigenic E. coli was used as prophylaxis against E. coli challenge in volunteers. Lyophilized milk immunoglobulins were… CONTINUE READING

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